MicroRNA-205 Inhibits Src-Mediated Oncogenic Pathways in Renal Cancer

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MicroRNA-205 inhibits Src-mediated oncogenic pathways in renal cancer.

The Src family of protein kinases (SFK) plays key roles in regulating fundamental cellular processes, including cell growth, differentiation, cell shape, migration, and survival, and specialized cell signals in various malignancies. The pleiotropic functions of SFKs in cancer make them promising targets for intervention. Here, we sought to investigate the role of microRNA-205 (miR-205) in inhib...

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Molecular and Cellular Pathobiology MicroRNA-205 Inhibits Src-Mediated Oncogenic Pathways in Renal Cancer

The Src family of protein kinases (SFK) plays key roles in regulating fundamental cellular processes, including cell growth, differentiation, cell shape, migration, and survival, and specialized cell signals in various malignancies. The pleiotropic functions of SFKs in cancer make them promising targets for intervention. Here, we sought to investigate the role of microRNA-205 (miR-205) in inhib...

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MicroRNA-205 inhibits renal cells apoptosis via targeting CMTM4

Objective(s):MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression. They have important roles in kidney development, homeostasis and disease, and participate in the onset and progression of tubulointerstitial sclerosis and end-stage glomerular lesions that occur in various forms of chronic kidney disease (CKD). In the present study, we elucidated the role of microR...

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microrna-205 inhibits renal cells apoptosis via targeting cmtm4

objective(s):micrornas (mirnas) are small non-coding rna molecules that regulate gene expression. they have important roles in kidney development, homeostasis and disease, and participate in the onset and progression of tubulointerstitial sclerosis and end-stage glomerular lesions that occur in various forms of chronic kidney disease (ckd). in the present study, we elucidated the role of micror...

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MicroRNA-205 inhibits renal cells apoptosis via targeting CMTM4

OBJECTIVES MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression. They have important roles in kidney development, homeostasis and disease, and participate in the onset and progression of tubulointerstitial sclerosis and end-stage glomerular lesions that occur in various forms of chronic kidney disease (CKD). In the present study, we elucidated the role of microRNA...

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ژورنال

عنوان ژورنال: Cancer Research

سال: 2011

ISSN: 0008-5472,1538-7445

DOI: 10.1158/0008-5472.can-10-3666